Faculty Profile

Michael Insana

Michael Insana
Michael Insana
Donald Biggar Willett Professor in Engineering
  • Beckman Institute for Advanced Science and Technology
  • Bioengineering
  • Mayo-Illinois Alliance
4247 Beckman Institute MC 251
405 N. Mathews
Urbana Illinois 61801
(217) 244-0739


  • Beckman Institute for Advanced Science and Technology
  • Bioengineering
  • Mayo-Illinois Alliance
  • Bioengineering
  • Department Office

Primary Research Area

  • Bioimaging at Multi-Scale


  • Ph.D. Medical Physics, University of Wisconsin, Madison 1983

For more information

Professional Registrations

  • Biomedical Engineering Society, 2008 - present

Teaching Statement

Graduate course BIOE 504 "Analytic Methods for Bioengineering" is a core course taken by all bioengineering graduate students. The goal is to review mathematical and computation methods applied to biological systems design and evaluation. It includes linear systems, probability, random processes, differential equations, control systems, and data modeling.

Undergraduate course BIOE 298 "Math Methods for Device Evaluation and Pathway Modeling" is an introduction to linear algebra with applications to instrumentation evaluation and systems biology.

Resident Instruction

  • BIOE 198 - Data Analytics (UIUC) - 2018 to present
  • BIOE 504 - Analytical Methods in Bioengineering (UIUC) - 2006 to present

Research Statement

Laboratory research focuses on the development of novel ultrasonic instrumentation and methods for imaging soft tissue microstructure, viscoelasticity and blood flow. The goal is to understand basic mechanisms of cancerous lesion formation, metastatic progression, responses to therapy, and sources of image contrast. Research includes the fundamentals of imaging system design and performance evaluation, signal processing, detection and estimation. The lab uses polymer hydrogels to develop models of visco- and poroelastic behavior of soft tissues for cancer imaging. Insana's lab also investigates spatio-temporal filtering for noise reduction and enhanced spatial resolution with applications in breast elasticity imaging and arterial-wall shear-stress estimation.

Graduate Research Opportunities

I supervise 5 graduate students. We continue to publish together, attend conferences, and I graduate an average of 1 MS or PhD student each year.

Research Interests

  • Medical imaging systems development particularly for applications breast cancer, vascular disease, and kidney disease. Ultrasonics, signal processing, signal detection, elasticity imaging, soft tissue biomechanics, polymer mechanics, complex system modeling.

Research Areas

  • Complex system modeling
  • Medical imaging systems - particularly for applications in breast cancer and vascular and kidney diseases
  • Polymer mechanics
  • Signal detection
  • Signal processing
  • Soft tissue biomechanics
  • Ultrasound

Research Topics

  • Bioimaging at Multi-Scale

Books Edited or Co-Edited (Original Editions)

  • M.F. Insana and S.A. Wickline (editors), Proceedings of the IEEE, Volume 96, No. 3, Special Issue: "Multimodality Biomolecular Imaging", March Issue 2008.

Selected Articles in Journals

Articles in Conference Proceedings

Journal Editorships

  • Editor-in-Chief, IEEE Trans Medical Imaging (2015-).

Professional Societies

  • Biomedical Engineering Society, 2008 -

Service on Department Committees

  • Interim Department Head, Bioengineering (2008-2010)


  • Fellow of the IEEE - 2012
  • Fellow of the Acoustical Society of America - 2009