Faculty Profile

Rohit Bhargava

Bioengineering
Rohit Bhargava
Rohit Bhargava
Founder Professor in Bioengineering and Bliss Faculty Scholar
  • Beckman Institute for Advanced Science and Technology
  • Bioengineering
  • Cancer Community @ Illinois
  • Chemical and Biomolecular Engineering
  • Chemistry
  • Electrical and Computer Engineering
  • Micro and Nanotechnology Laboratory
4265 Beckman Institute MC 251
405 N. Mathews
Urbana Illinois 61801
(217) 265-6596

Affiliation

  • Beckman Institute for Advanced Science and Technology
  • Bioengineering
  • Cancer Community @ Illinois
  • Chemical and Biomolecular Engineering
  • Chemistry
  • Electrical and Computer Engineering
  • Micro and Nanotechnology Laboratory

Primary Research Area

  • Cell and tissue engineering - Tumor microenvironments

Education

  • Ph.D. (Macromolecular Science and Engineering), Case Western Reserve University, Cleveland, Ohio, 2000.

Academic Positions

  • Co-Leader, HABITS--Health: Attitudes, Biology, Information Technology, Society Initiative, Beckman Institute, 2010-2015
  • Affiliate Faculty, Computational Science and Engineering Program, University of Illinois at Urbana-Champaign, Urbana, IL, 2006-present
  • Faculty, Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL, 2008- present
  • Research Affiliate, Mills Breast Cancer Institute, Carle Foundation Hospital, 2010-present
  • Affiliate Faculty, Department of Mechanical Science & Engineering, Electrical & Computer Engineering, Chemical & Biomolecular Engineering,University of Illinois at Urbana-Champaign, Urbana, IL, 2011-present
  • Associate Director and member, University of Illinois Cancer Center, University of Illinois at Urbana-Champaign, Urbana, IL, 2011-2016
  • Full-time faculty, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 2005-present
  • Assistant Professor, Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 2005-2011
  • Associate Professor, Department of Bioengineering,University of Illinois at Urbana-Champaign, Urbana, IL, 2011-2012
  • Bliss Faculty Scholar, University of Illinois at Urbana-Champaign, Urbana, IL., 2012-2016
  • Director, Cancer Center at Illinois, University of Illinois at Urbana-Champaign, 2016-present
  • Founder Professor in Engineering, College of Engineering, University of Illinois at Urbana-Champaign, Urbana, IL. 2016-present
  • Professor, University of Illinois at Urbana-Champaign, Urbana, IL. 2012-present

For more information

Other Professional Employment

  • Research Assistant, NSF Center for Advanced Liquid Crystalline Optical Materials, Case Western Reserve University, Cleveland, OH, October 1996-February 2000.
  • Research Fellow, Laboratory of Chemical Physics, NIDDK, National Institutes of Health, Bethesda, MD, March 2000-August 2005.

Undergraduate Research Opportunities

Undergraduate researchers in Prof. Bhargava's group help in developing methods for diagnosing and grading cancer, in developing nanoparticle probes for optical imaging, in tissue engineering, and in developing new computer software.

Research Interests

  • Biological Samples: Generation and Processing
  • Spontaneous Raman Spectrometer
  • Microreactors for Continuous Fluidic Synthesis of NanoImaging Probes
  • 3D Printing for Cell Culture Systems
  • High Quality Tissue Classification
  • QCL Widefield
  • Discrete Frequency (DF-IR)
  • Agilent LDIR
  • Nano Scale IR Tomography
  • Cancer nanotechnology
  • Cancer pathology
  • Fourier transform infrared spectroscopy
  • Stimulated Raman Scattering Microscopy (SRSM)

Research Areas

  • Big Data
  • Bioinformatics
  • Biomolecular engineering
  • Biotechnology
  • Cell and molecular engineering
  • Chemical biosensors
  • Computational bioengineering
  • Early cancer detection
  • Micro and molecular technologies
  • Microfabrication
  • Nanoparticle bioimaging probes
  • Optical biosensors
  • Optical diagnostics for cancer
  • Quantum dot chemistry and physics
  • Signal processing
  • Tumor microenvironments

Research Topics

  • Bio-Micro and Nanotechnology

Books Edited or Co-Edited (Original Editions)

  • R. Bhargava, I. W. Levin, eds. Spectrochemical Analyses Using Multichannel Infrared Detectors, Blackwell Publishing Ltd., Oxford, UK, 2005.

Chapters in Books

  • R. Bhargava, I. W. Levin "Recent developments in Fourier transform infrared (FTIR) microspectroscopic methods for biomedical analyses: From single-point detection to two-dimensional imaging" Biomedical Photonics Handbook, T. Vo-Dinh, ed., CRC Press, Boca Raton, FL (2002).
  • R. Bhargava, I. W. Levin "Mid-infrared spectroscopic imaging with multichannel detectors" Spectrochemical Analyses Using Infrared Multichannel Detectors, R. Bhargava, I. W. Levin, eds., Blackwell Publishing (2005).
  • R. Bhargava, M. D. Schaeberle, I. W. Levin "Raman and mid-infrared microspectroscopic imaging" Vibrational Spectroscopy of Biological and Polymeric Materials, V. G. Gregariou, M. Braiman, eds., CRC Press, Boca Raton, FL (2005).
  • R. Bhargava, I. W. Levin, "Infrared spectroscopic imaging protocols for high-throughput histopathology" Vibrational Spectroscopy for Medical Diagnosis, M. Diem, P. R. Griffiths, J. Chalmers, eds., John Wiley and Sons, Chichester, UK (2008).
  • A. K. Kodali, R. Bhargava "Nanostructured probes to enhance optical and vibrational spectroscopic imaging for biomedical applications" The Oxford Handbook of Nanoscience and Technology: Vol. III: Applications, Y. Y. Fu, A. Narlikar, eds., Oxford University Press, Oxford, UK (2010).
  • R. K. Reddy, R. Bhargava ￿Chemometric methods for biomedical vibrational spectroscopy and imaging￿ Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields, M.D. Morris, P. Matousek, eds., Springer-Verlag, Berlin, Germany (2010).
  • F. N. Pounder, R. Bhargava ￿Toward automated breast histopathology using mid-IR spectroscopic imaging￿ Vibrational Spectroscopic Imaging for Biomedical Applications, G. Srinivasan, ed., McGraw-Hill, New York, NY (2010).
  • M. J. Walsh, R. Bhargava ￿Infrared spectroscopic imaging: An integrative approach to pathology￿ Nanobiophotonics, G. Popescu, ed., McGraw-Hill, New York, NY (2010).
  • K. Yeh, R. K. Reddy, R. Bhargava ￿Fourier transform infrared spectroscopic imaging￿ Emerging Imaging Technologies in Medicine, M. A. Anastasio, P. La Riviere, eds., Taylor Francis/CRC Press, Boca Raton, FL (2012).
  • S. Biswas, M. J. Walsh, R. Bhargava ￿Fourier transform infrared (Ft-Ir) spectroscopic imaging for solid tumor histopathology￿ Optical Spectroscopy and Computational Methods in Biology and Medicine, Challenges and Advances in Computational Chemistry and Physics, M. Baranska, ed., Springer (2014).

Selected Articles in Journals

  • U. S. Agarwal, R. Bhargava, R. A. Mashelkar ￿Brownian dynamics simulation of a polymer molecule in solution under elongational flow￿ J. Chem. Phys. 108, 1610￿1617 (1998).
  • R. Bhargava, S.-Q. Wang, J. L. Koenig ￿FT-IR imaging of the interface in multicomponent systems using optical effects induced by differences in refractive index￿ Appl. Spectrosc. 52, 323￿328 (1998) [Accelerated Publication].
  • R. Bhargava, S.-Q. Wang, J. L. Koenig ￿FTIR imaging studies of a new two-step process to produce polymer dispersed liquid crystals￿ Macromolecules 32, 2748￿2760 (1999).
  • R. Bhargava, T. Ribar, J. L. Koenig ￿Towards faster FT-IR imaging by reducing noise￿ Appl. Spectrosc. 53, 1313￿1322 (1999).
  • R. Bhargava, S.-Q. Wang, J. L. Koenig ￿Studying polymer-dispersed liquid-crystal formation by FTIR spectroscopy. 2. Phase separation and ordering￿ Macromolecules 32, 8989￿8995 (1999).
  • R. Bhargava, S.-Q. Wang, J. L. Koenig ￿Studying polymer-dispersed liquid-crystal formation by FTIR spectroscopy. 1. Monitoring curing reactions￿ Macromolecules 32, 8982￿8988 (1999).
  • R. Bhargava, S.-Q. Wang, J. L. Koenig ￿Route to higher fidelity FT-IR imaging￿ Appl. Spectrosc. 54, 486￿495 (2000).
  • R. Bhargava, B. G. Wall, J. L. Koenig ￿Comparison of the FT-IR mapping and imaging techniques applied to polymeric systems￿ Appl. Spectrosc. 54, 470￿479 (2000).
  • R. Bhargava, S.-Q. Wang, J. L. Koenig ￿Processing FT-IR imaging data for morphology visualization￿ Appl. Spectrosc. 54, 1690￿1706 (2000).
  • T. Ribar, R. Bhargava, J. L. Koenig ￿FT-IR imaging of polymer dissolution by solvent mixtures. 1. Solvents￿ Macromolecules 33, 8842￿8849 (2000).
  • R. Bhargava, D. C. Fernandez, M. D. Schaeberle, I. W. Levin ￿Effect of focal plane array cold shield aperture size on Fourier transform infrared micro-imaging spectrometer performance￿ Appl. Spectrosc. 54, 1743￿1750 (2000).
  • J. L. Koenig, S.-Q. Wang, R. Bhargava ￿FTIR images: A new technique produces images worth a thousand spectra￿ Anal. Chem. 73, 361A￿369A (2001) [Cover Feature Article].
  • R. Bhargava, M. D. Schaeberle, D. C. Fernandez, I. W. Levin ￿Novel route to faster Fourier transform infrared spectroscopic imaging￿ Appl. Spectrosc. 55, 1079￿1084 (2001).
  • T. Ribar, J. L. Koenig, R. Bhargava ￿FTIR imaging of polymer dissolution. 2. Solvent/nonsolvent mixtures￿ Macromolecules 34, 8340￿8346 (2001).
  • R. Bhargava, I. W. Levin ￿FTIR imaging: Theory and practice￿ Anal. Chem. 73, 5157￿5167 (2001).
  • R. Bhargava, D. C. Fernandez, M. D. Schaeberle, I. W. Levin ￿Theory and application of gain ranging to Fourier transform infrared spectroscopic imaging￿ Appl. Spectrosc. 55, 1580￿1589 (2001).
  • I. W. Levin, R. Bhargava ￿Fourier transform infrared spectroscopic imaging of biological tissue￿ Trends Appl. Spectrosc. 3, 57￿71 (2001).
  • R. Bhargava, I. W. Levin ￿Effective time averaging of multiplexed measurements: A critical analysis￿ Anal. Chem. 74, 1429￿1435 (2002).
  • S. W. Huffman, R. Bhargava, I. W. Levin ￿A generalized implementation of rapid-scan Fourier transform infrared spectroscopic imaging￿ Appl. Spectrosc. 56, 965￿969 (2002) [Accelerated Publication].
  • R. Bhargava, I. W. Levin ￿Noninvasive imaging of molecular dynamics in heterogeneous materials￿ Macromolecules 36, 92￿96 (2003) [Featured in Anal. Chem. News Section, July 2003].
  • R. Bhargava, I. W. Levin ￿Time-resolved Fourier transform infrared spectroscopic imaging￿ Appl. Spectrosc. 57, 357￿366 (2003) [Accelerated Publication].
  • R. Bhargava, S.-Q. Wang, J. L. Koenig ￿FTIR microspectroscopy of polymeric systems￿ Adv. Polym. Sci. 163, 137￿191 (2003).
  • R. Bhargava, I. W. Levin ￿Probing the structure and dynamics of macromolecular composites by infrared spectroscopy and imaging￿ Vib. Spectrosc. 34, 13￿24 (2004) [Invited Special Issue: Prominent Young Vibrational Spectroscopists].
  • R. Bhargava, I. W. Levin ￿Enhanced time-resolved Fourier transform infrared spectroscopic imaging for reversible dynamics￿ J. Phys. Chem. A 108, 3896￿3901 (2004).
  • R. Bhargava, I. W. Levin ￿Gram-Schmidt orthogonalization for rapid reconstructions of Fourier transform infrared spectroscopic imaging data￿ Appl. Spectrosc. 58, 995￿1000 (2004).
  • I. W. Levin, R. Bhargava ￿Fourier transform infrared vibrational spectroscopic imaging: Integration of microscopy and molecular recognition￿ Annu. Rev. Phys. Chem. 56, 429￿474 (2005).
  • D. C. Fernandez,* R. Bhargava,* S. M. Hewitt, I. W. Levin ￿Infrared spectroscopic imaging for histopathologic recognition￿ Nat. Biotechnol. 23, 469￿474 (2005) [*equal first authors].
  • R. Bhargava, D. C. Fernandez, S. M. Hewitt, I. W. Levin ￿High throughput assessment of cells and tissues: Bayesian classification of spectral metrics from infrared vibrational spectroscopic imaging data￿ Biochim. Biophys. Acta 1758, 830￿845 (2006).
  • R. Bhargava, S. M. Hewitt, I. W. Levin ￿Reply to Unrealistic expectations for IR microspectroscopic imaging￿ Nat. Biotechnol. 25, 31￿33 (2007).
  • G. Srinivasan, R. Bhargava ￿Fourier transform infrared spectroscopic imaging: the emerging evolution from a microscopy tool to a cancer imaging modality￿ Spectroscopy, 22, 40￿51 (2007).
  • R. Bhargava ￿Towards a practical Fourier transform infrared chemical imaging protocol for cancer histopathology￿ Anal. Bioanal. Chem. 389, 1155￿1169 (2007).
  • K. Park, J. Lee, R. Bhargava, W. P. King ￿Routine femtogram-level chemical analyses using vibrational spectroscopy and self-cleaning scanning probe microscopy tips￿ Anal. Chem. 80, 3221￿3228 (2008).
  • X. Llor￿A. Priya, R. Bhargava ￿Observer-invariant histopathology using genetics-based machine learning￿ Nat. Computing 8, 101￿120 (2009).
  • R. Bhargava, R. S. Perlman, D. C. Fernandez, I. W. Levin, E. G. Bartick ￿Non-invasive detection of superimposed latent fingerprints and inter-ridge trace evidence by infrared spectroscopic imaging￿ Anal. Bioanal. Chem. 394, 2069￿2075 (2009).
  • B. J. Davis, P. S. Carney, R. Bhargava ￿Theory of mid-infrared absorption microspectroscopy. I. Homogeneous samples￿ Anal. Chem. 82, 3474￿3486 (2010) doi:10.1021/ac902067p.
  • B. J. Davis, P. S. Carney, R. Bhargava ￿Theory of mid-infrared absorption microspectroscopy. II. Heterogeneous samples￿ Anal. Chem. 82, 3487￿3499 (2010) doi:10.1021/ac902068e.
  • R. Kong, R. K. Reddy, R. Bhargava ￿Characterization of tumor progression in engineered tissue using infrared spectroscopic imaging￿ Analyst 135, 1569￿1578 (2010) doi:10.1039/c0an00112k.
  • M. V. Schulmerich, R. Reddy, A. K. Kodali, L. J. Elgass, K. Tangella, R. Bhargava ￿Dark field Raman microscopy￿ Anal. Chem. 82, 6273￿6280 (2010) doi:10.1021/ac1014194.
  • A. K. Kodali, M. Schulmerich, J. Ip, G. Yen, B. T. Cunningham, R. Bhargava ￿Narrowband midinfrared reflectance filters using guided mode resonance￿ Anal. Chem. 82, 5697￿5706 (2010) doi:10.1021/ac1007128.
  • A. K. Kodali, X. Llora, R. Bhargava ￿Optimally designed nanolayered metal-dielectric particles as probes for massively multiplexed and ultrasensitive molecular assays￿ Proc. Natl. Acad. Sci. 107, 13620￿13625 (2010) doi:10.1073/pnas.1003926107.
  • R. K. Reddy, R. Bhargava ￿Accurate histopathology from low signal-to-noise ratio spectroscopic imaging data￿ Analyst 135, 2818￿2825 (2010) doi:10.1039/C0AN00350F.
  • A. K. Kodali, M. V. Schulmerich, R. Palekar, X. Llora, R. Bhargava ￿Optimized nanospherical layered alternating metal-dielectric probes for optical sensing￿ Opt. Express 18, 23302￿23313 (2010).
  • J. G. Moreno-Torres, X. Llor￿D. E. Goldberg, R. Bhargava ￿On the homogenization of data from two laboratories using genetic programming￿ Lec. Notes Comp. Sci. 6471, 185￿197 (2010) doi:10.1007/978-3-642-17508-4_12.
  • B. Kwon, C. Wang, K. Park, R. Bhargava, W. P. King ￿Thermomechanical sensitivity of microcantilevers in the mid-infrared spectral region￿ Nano Micro Thermophys. Eng. 15, 16￿28 (2011).
  • B. J. Davis, P. S. Carney, R. Bhargava ￿Theory of infrared microspectroscopy for intact fibers￿ Anal. Chem. 83, 525￿532 (2011).
  • J. T. Kwak, S. M. Hewitt, S. Sinha, R. Bhargava ￿Multimodal microscopy for automated histologic analysis of prostate cancer￿ BMC Cancer 11, 62 (2011) [Designated ￿Highly Accessed￿]. * Author profile by M. Baker Nat. Methods 8, 363 (2011) * News and Views: F. L. Martin ￿Shining a new light into molecular workings￿ Nat. Methods 8, 385￿387 (2011)
  • M. J. Nasse, M. J. Walsh, E. C. Mattson, R. Reininger, A. Kajdacsy-Balla, V. Macias, R. Bhargava,* C. J. Hirschmugl* ￿High-resolution Fourier transform infrared chemical imaging with multiple synchrotron beams￿ Nat. Methods 8, 413￿416 (2011) doi:10.1038/NMETH.1585 [*Joint corresponding authors].
  • R. Kong, R. Bhargava ￿Characterization of porcine skin as a model for human transdermal diffusion￿ Analyst 136, 2359￿2366 (2011) doi:10.1039/C1AN15111H.
  • S. E. Holton, M. J. Walsh, R. Bhargava ￿Subcellular localization of early biochemical transformations in cancer-activated fibroblasts using high-resolution infrared spectroscopic imaging￿ Analyst 136, 2953￿2958 (2011) doi:10.1039/c1an15112f.
  • J. Yao, A.-P. Le, M. V. Schulmerich, J. Maria, T.-W. Lee, S. K. Gray, R. Bhargava, J. A. Rogers, R. G. Nuzzo ￿Soft embossing of nanoscale optical and plasmonic structures in glass￿ ACS Nano 5, 5763￿5774 (2011) doi:10.1021/nn201464t.
  • S. E. Holton, M. J. Walsh, A. Kajdacsy-Balla, R. Bhargava ￿Label-free characterization of cancer-activated fibroblasts in cell culture and clinical tissues using infrared spectroscopic imaging￿ Biophys. J. 101, 1513￿1521 (2011) doi:10.1016/j.bpj.2011.07.055.
  • A. K. Kodali, R. Bhargava ￿Effect of non-specificity in shape, size, and dielectric properties on electromagnetic extinction and optical field enhancement from spherical nanolayered metal-dielectric particles" Theor. Chem. Acc. 130, 991￿1000 (2011) [Invited] doi:10.1007/s00214-011-1038-1.
  • D. Chanda, K. Shigeta, T. Truong, E. Lui, A. Mihi, M. V. Schulmerich, P. V. Braun, R. Bhargava, J. A. Rogers ￿Coupling of plasmonic and optical cavity modes in quasi-three-dimensional plasmonic crystals￿ Nat. Commun. 2, 479 (2011) doi:10.1038/ncomms1487.
  • J.-N. Liu, M. V. Schulmerich, R. Bhargava, B. T. Cunningham ￿Optimally designed narrowband mid-infrared guided-mode resonance reflectance filters for mid-infrared optical spectroscopy￿ Opt. Express 19, 24182-24197 (2011) doi:10.1364/OE.19.024182.
  • D. M. Mahr, R. Bhargava, M. F. Insana ￿Three-dimensional in silico breast phantoms for multimodal image simulations￿ IEEE Trans. Med. Imaging 31, 689￿697 (2012) doi:10.1109/TMI.2011.2175401.
  • B. Kwon, M. Rosenberger, R. Bhargava, D. G. Cahill, W. P. King ￿Dynamic thermomechanical response of bimaterial microcantilevers to periodic heating by infrared radiation￿ Rev. Sci. Instr. 83, 015003 (2012) doi:10.1063/1.3680107.
  • J. T. Kwak, R. K. Reddy, S. Sinha, R. Bhargava ￿Analysis of variance in spectroscopic imaging data from human tissues￿ Anal. Chem. 84, 1063￿1069 (2012) doi:10.1021/ac2026496.
  • B. Kwon, M. V. Schulmerich, L. J. Elgass, R. Kong, S. E. Holton, R. Bhargava, W. P. King ￿Infrared microspectroscopy combined with conventional atomic force microscopy￿ Ultramicroscopy 116, 56-61 (2012).
  • M. J. Walsh, S. E. Holton, A. Kajdacsy-Balla, R. Bhargava ￿Attenuated total reflectance Fourier transform infrared spectroscopic imaging for comprehensive breast tissue histopathology￿ Vib. Spectrosc. 60, 23￿28 (2012) doi:10.1016/j.vibspec.2012.01.010. doi:10.1109/JSTQE.2011.2182635.
  • M. J. Walsh, R. K. Reddy, R. Bhargava ￿Label-free biomedical imaging with mid-infrared microspectroscopy￿ IEEE J. Sel. Top. Quant. 18, 1502￿1513 (2012) [Invited]
  • N. Lu, S. E. Mylon, R. Kong, R. Bhargava, J. L. Zilles, T. H. Nguyen ￿Interactions between dissolved natural organic matter and adsorbed DNA and their effect on natural transformation of Azotobacter vinelandii￿ Sci. Total Environ. 426, 430￿435 (2012).
  • S. A. Odom, T. P. Tyler, M. M. Caruso, J. A. Ritchey, M. V. Schulmerich, S. J. Robinson, R. Bhargava, N. R. Sottos, S. R. White, M. C. Hersam, J. S. Moore ￿Autonomic restoration of electrical conductivity using polymer-stabilized carbon nanotube and graphene microcapsules￿ Appl. Phys. Lett. 101, 043106 (2012).
  • R. Ambekar, T.-Y. Lau, M. Walsh, R. Bhargava, K. C. Toussaint Jr ￿Quantifying collagen structure in breast biopsies using second-harmonic generation imaging￿ Biomed. Opt. Express 3, 2021￿2035 (2012).
  • M. V. Schulmerich, M. J. Walsh, M. K. Gelber, R. Kong, M. R. Kole, S. K. Harrison, J. McKinney, D. Thompson, L. S. Kull, R. Bhargava ￿Protein and oil composition predictions of single soybeans by transmission Raman spectroscopy￿ J. Agric. Food. Chem. 60, 8097￿8102 (2012).
  • R. Bhargava ￿Infrared spectroscopic imaging: The next generation￿ Appl. Spectrosc. 66, 1091￿1120 (2012) [Invited Focal Point Article].
  • M. R. Kole, R. K. Reddy, M. V. Schulmerich, M. K. Gelber, R. Bhargava ￿Discrete frequency infrared microspectroscopy and imaging with a tunable quantum cascade laser￿ Anal. Chem. 84, 10366￿10372 (2012) doi:dx.doi.org/10.1021/ac302513f.
  • R. K. Reddy, M. J. Walsh, M. V. Schulmerich, P. S. Carney, R. Bhargava ￿High-definition infrared spectroscopic imaging￿ Appl. Spectrosc. 67, 93￿105 (2013).
  • J. G. Moreno-Torres, X. Llor￿D. E. Goldberg, R. Bhargava ￿Repairing fractures between data using genetic programming-based feature extraction: A case study in cancer diagnosis￿ Info. Sci. 222, 805￿823 (2013).
  • B. Kwon, M. V. Schulmerich, R. Bhargava, W. P. King ￿Infrared emission from heated microcantilevers￿ Nanosc. Microsc. Thermophys. Eng. 17, 141￿153 (2013).
  • A. Abouimrane, S. A. Odom, H. Tavassol, M. V. Schulmerich, H. Wu, R. Bhargava, A .A. Gewirth, J. S. Moore, K. Amine ￿3-Hexylthiophene as a stabilizing additive for high voltage cathodes in lithium-ion batteries￿ J. Electrochem. Soc. 160, A268￿A271 (2013).
  • S. T. Sivapalan, B. M. DeVetter, T. K. Yang, T. van Dijk, M. V. Schulmerich, P. S. Carney, R. Bhargava, C. J. Murphy ￿Off-resonance SERS from gold nanorod suspensions as a function of aspect ratio: Not what we thought￿ ACS Nano 7, 2099￿2105 (2013).
  • A. K. Kodali, M. Schulmerich, R. Palekar, R. Bhargava ￿Sculpting the analytical volume in and around nanoparticle sensors using a multilayer geometry￿ Anal. Chem. 85, 3842￿3848 (2013).
  • Y. Liu, C. Zhang, D. Hu, M. S. Kuhlenschmidt, T. B. Kuhlenschmidt, S. E. Mylon, R. Kong, R. Bhargava, T. H. Nguyen ￿Role of collector alternating charged patches on transport of Cryptosporidium parvum oocyst in a patchwise charged heterogeneous micromodel￿ Environ. Sci. Technol., 47, 2670￿2678 (2013) doi:10.1021/es304075j.
  • A. B. Shah, S. T. Sivapalan, B. M. DeVetter, T. K. Yang, J. Wen, R. Bhargava, C. J. Murphy, J.-M. Zuo ￿High-index facets in gold nanocrystals elucidated by coherent electron diffraction￿ Nano Lett. 13, 1840￿1846 (2013).
  • T. van Dijk, S. T. Sivapalan, B. M. DeVetter, M. V. Schulmerich, T. K. Yang, C. J. Murphy, R. Bhargava, P. S. Carney ￿Competition between extinction and enhancement in surface-enhanced Raman spectroscopy￿ J. Phys. Chem. Lett. 4, 1193￿1196 (2013).
  • T. van Dijk, D. Mayerich, P. S. Carney, R. Bhargava ￿Recovery of absorption spectra from Fourier transform infrared (FT-IR) microspectroscopic measurements of intact spheres￿ Appl. Spectrosc. 67, 546￿552 (2013).
  • D. Mayerich, M. J. Walsh, M. V. Schulmerich, R. Bhargava ￿Real-time interactive data mining for chemical imaging information: Application to automated histopathology￿ BMC Bioinformatics 14, 156 (2013) [designated ￿highly accessed￿].
  • S. T. Sivapalan, B. M. DeVetter, T. K. Yang, M. V. Schulmerich, R. Bhargava, C. J. Murphy ￿Surface-enhanced Raman spectroscopy of polyelectrolyte-wrapped gold nanoparticles in colloidal suspension￿ J. Phys. Chem. C 117, 10677￿10682 (2013).
  • T. van Dijk, D. Mayerich, R. Bhargava, P. S. Carney ￿Rapid spectral-domain localization￿ Opt. Express 21, 12822￿12830 (2013).
  • B. Kwon, J. Jiang, M. V. Schulmerich, Z. Xu, R. Bhargava, G. L. Liu, W. P. King ￿Bimaterial microcantilevers with black silicon nanocone arrays￿ Sens. Actuators, A 199, 143￿148 (2013).
  • M. V. Schulmerich, M. K. Gelber, H. M. Azam, S. K. Harrison, J. McKinney, D. Thompson, B. Owen, L. S. Kull, R. Bhargava ￿Amino acid quantification in bulk soybeans by transmission Raman spectroscopy￿ Anal. Chem. 85, 11376￿11381 (2013).
  • B. Kwon, M. Seong, J.-N. Liu, M. R. Rosenberger, M. V. Schulmerich, R. Bhargava, B. T. Cunningham, W. P. King ￿Large infrared absorptance of bimaterial microcantilevers based on silicon high contrast gratings￿ J. Appl. Phys. 114, 153511 (2013) doi:10.1063/1.4825313.
  • B. M. DeVetter, R. Bhargava, C. J. Murphy ￿Computational study of the surface-enhanced Raman scattering from silica-coated silver nanowires￿ Photochem. Photobiol. 90, 415￿418 (2014).
  • D. Mayerich, T. van Dijk, M. J. Walsh, M. V. Schulmerich, P. S. Carney, R. Bhargava ￿On the importance of image formation optics in the design of infrared spectroscopic imaging systems￿ Analyst 139, 4031￿4036 (2014).
  • S. E. Holton, A. Bergamaschi, B. S. Katzenellenbogen, R. Bhargava ￿Integration of molecular profiling and chemical imaging to elucidate fibroblast-microenvironment impact on cancer cell phenotype and endocrine resistance in breast cancer￿ PLOS ONE 9(5), e96878 (2014).
  • M. J. Baker, J. Trevisan, P. Bassan, R. Bhargava, H. J. Butler, K. M. Dorling, P. R. Fielden, S. W. Fogarty, N. J. Fullwood, K. A. Heys, C. Hughes, P. Lasch, P. L. Martin-Hirsch, B. Obinaju, G. D. Sockalingum, J. Sul￿uso, R. J. Strong, M. .J. Walsh, B. R. Wood, P. Gardner, F. L. Martin ￿Using Fourier transform IR spectroscopy to analyze biological materials￿ Nat. Protocols 9, 1771￿1791 (2014) doi:10.1038/nprot.2014.110.
  • A. Rosenberg, J. Surya, R. Liu, W. Streyer, S. Law, L. S. Leslie, R. Bhargava, D. Wasserman ￿Flat mid-infrared composite plasmonic materials using lateral doping-patterned semiconductors￿ J. Optics 16, 094012 (2014).
  • J.-N. Liu, M. V. Schulmerich, R. Bhargava, B. T. Cunningham ￿Sculpting narrowband Fano resonances inherent in the large-area mid-infrared photonic crystal microresonators for spectroscopic imaging￿ Opt. Express 22, 18142￿18158 (2014).
  • B. M. DeVetter, S. T. Sivapalan, D. D. Patel, M. V. Schulmerich, C. J. Murphy, R. Bhargava ￿Observation of molecular diffusion in polyelectrolyte-wrapped SERS nanoprobes￿ Langmuir 30, 8931￿8937 (2014).
  • T. van Dijk, D. Mayerich, P.S. Carney,￿R. Bhargava￿"Understanding the optics-sample interaction in infrared spectroscopic imaging"￿Analyst￿139, 4031-4036 (2015).
  • K. Yeh, S. Kenkel, J.-N. Liu, R. Bhargava ￿Fast infrared chemical imaging with a quantum cascade laser￿ Anal. Chem. 87, 485￿493 (2015).
  • D. Mayerich, M.J. Walsh, A. Kajdacsy-Balla, P.S. Ray, S. M. Hewitt, R. Bhargava ￿Stain-less staining for computed molecular histopathology￿ Technology 3, 27-31 (2015).
  • J. T. Kwak, A. Kajdacsy-Balla, V. Macias, M. J. Walsh, S. Sinha, R. Bhargava ￿Improving prediction of prostate cancer recurrence using chemical imaging￿ Sci. Rep. 5, 8758 (2015).
  • B. Chng, R. Bhargava, P. S. Carney ￿Enhancement and extinction effects in surface-enhanced stimulated Raman spectroscopy￿ Phys. Chem. Chem. Phys. 17, 21348-21355 (2015). DOI: 10.1039/c4cp05089d
  • M. K. Gelber, R. Bhargava ￿Monolithic multilayer microfluidics via sacrificial molding of 3D-printed isomalt￿ Lab Chip 15, 1736￿1741 (2015). DOI: 10.1039/c4lc01392a.
  • B. M. DeVetter, P. Mukherjee, C. J. Murphy, R. Bhargava ￿Measuring binding kinetics of aromatic thiolated molecules with nanoparticles via surface-enhanced Raman spectroscopy￿ Nanoscale 7, 8766-8775 (2015) DOI: 10.1039/C5NR01006C
  • S. Tiwari, V.B. Reddy, R. Bhargava, J. Raman ￿Computational Chemical Imaging for Cardiovascular Pathology: Chemical Microscopic Imaging Accurately Determines Cardiac Transplant Rejection￿ PLoS One 10, e0125183 (2015). DOI: 10.1371/journal.pone.0125183
  • J. Han, W. Qiu, S. Tiwari, R. Bhargava, W. Gao, B. Xing ￿Consumer-grade polyurethane foam functions as a large and selective absorption sink for bisphenol A in aqueous media￿ J. Mater. Chem. A 3, 8870-8881 (2015).
  • B. Deutsch, R. K. Reddy, D. Mayerich, R. Bhargava, P. S. Carney ￿Compositional prior information in computed infrared spectroscopic imaging￿ J. Opt. Soc. Am. A 32, 1126-1131 (2015).
  • L. S. Leslie, T. P. Wrobel, D. Mayerich, S. Bindra, R. Emmadi, R. Bhargava ￿High definition infrared spectroscopic imaging for lymph node histopathology￿ PLoS One 10:e0127238 (2015). DOI: doi: 10.1371/journal.pone.0127238
  • P. Mukherjee, S. K. Misra, M. Gryka, H. Chang, S. Tiwari, W. L. Wilson, J. Scott, R. Bhargava, D. Pan ￿Tunable luminescent carbon nanospheres with well-defined nanoscale chemistry for synchronized imaging and therapy￿ Small 36, 4691￿4703 (2015) DOI: 10.1002/smll.201500728
  • S. Tiwari, R. Bhargava ￿Extracting Knowledge from Chemical Imaging Data Using Computational Algorithms for Digital Cancer Diagnosis￿ Yale J. Biol. Med. 88, 131￿143 (2015).
  • R. Bhargava, A. Madabhushi ￿Emerging themes in image informatics and molecular analysis for digital pathology￿ Annu. Rev. Biomed. Engr. 18, 387￿412 (2016) - invited
  • S.K. Misra, P. Mukherjee, A. Ohoka, A.S. Schwartz-Duval, S. Tiwari, R. Bhargava, D. Pan ￿Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized Doxorubicin and deuterated phospholipid vesicles￿ Nanoscale 8, 2826-2831 (2016)
  • S.E. Dubowsky, B. Deutsch, R. Bhargava, B. McCall ￿Infrared Emission Spectroscopy of Atmospheric-Pressure Ball Plasmoids￿ J. Mol. Spectrosc. 322, 1-8 (2016)
  • F.N. Keith, R.K. Reddy, R. Bhargava ￿Development of a practical spatial-spectral analysis protocol for breast histopathology using Fourier transform infrared spectroscopic imaging￿ Faraday Discuss. 187, 43-68 (2016) DOI: 10.1039/c5fd00199d ￿ invited
  • J. T. Kwak, S. M. Hewitt, A. Kajdacsy-Balla, S. Sinha, R. Bhargava ￿Automated prostate tissue referencing for cancer detection and diagnosis￿ BMC Bioinformatics 17, 227 (2016) DOI 10.1186/s12859-016-1086-6
  • T.P. Wrobel, M. Kole, R. Bhargava ￿Emerging trends and opportunities in discrete frequency infrared and Raman spectroscopic imaging￿ Spectroscopy 31, 28-45 (2016) ￿ Invited
  • S.K. Misra, P. Mukherjee, H-H. Chang, S. Tiwari, M. Gryka, R. Bhargava, D. Pan ￿Multi-functionality Redefined with Colloidal Carotene Carbon Nanoparticles for Synchronized Chemical Imaging, Enriched Cellular Uptake and Therapy￿ Sci. Rep. 6, Article 29299 (2016)
  • P. Mukherjee, S.J. Lim, T.P. Wrobel, R. Bhargava,* A.M. Smith* ￿Measuring and predicting the internal structure of semiconductor nanocrystals through Raman spectroscopy￿ J. Am. Chem. Soc. 138, 10887-10896 (2016) [*joint corresponding authors] DOI: 10.1021/jacs.6b03907
  • B.M. DeVetter, S. Kenkel, S. Mittal, R. Bhargava, T. Wrobel ￿Characterization of structure of low-e substrates and consequences for IR transflection measurements￿ Vib. Spectrosc. 91, 119-127 (2016) DOI: 10.1016/j.vibspec.2016.09.001
  • F. Ostadhossein, S.K. Misra, P. Mukherjee, A. Ostadhossein, E. Daza, S. Tiwari, S. Mittal, M.C. Gryka, R. Bhargava, D. Pan ￿Breast Cancer Therapy: Defined host-guest chemistry on Nanocarbon for sustained inhibition of cancer￿ Small 12, 5782-5782 (2016) DOI: 10.1002/smll.201601161
  • S. Tiwari, C. Hoke, V. Reddy, J. Raman, R. Bhargava ￿Translating infrared spectroscopic imaging for rapid analysis of biopsy samples using a discrete frequency approach￿ Anal. Chem. 88, 10183-10190 (2016) DOI: 10.1021/acs.analchem.6b02754
  • T.Q. Doan, L.S. Leslie, S.Y. Kim, R. Bhargava, S.R. White, N. Sottos ￿Characterization of core-shell microstructure and self-healing performance of electrospun fiber coatings￿ Polymer 107, 263-272 (2016)
  • S. Kang, S.E. Lehman, M.V. Schulmerich, A. Le, T. Lee, S.K. Gray, R. Bhargava, R.G. Nuzzo ￿Refractive index sensing and surface-enhanced Raman spectroscopy using silver￿gold layered bimetallic plasmonic crystals￿ Beilstein J Nanotechnol. 8, 2492￿2503 (2017). doi: 10.3762/bjnano.8.249
  • S. Berisha, T. van Dijk, R. Bhargava, P.S. Carney, D. Mayerich ￿BIM-Sim: Interactive Simulation of Broadband Imaging Using Mie Theory￿ Fron. Phys.: Opt. Phot. 5, 5 (2017) DOI: 10.3389/fphy.2017.00005
  • T.P. Wrobel, P. Mukherjee, R. Bhargava ￿Rapid visualization of macromolecular orientation by discrete mid-infrared spectroscopic imaging￿ Analyst 142, 75-79 (2017) DOI: 10.1039/c6an01086e.
  • M.K. Gelber, M.R. Kole, N. Kim, N. Aluru, R. Bhargava ￿Quantitative Chemical Imaging Within Non-Planar Microfluidics￿ Anal. Chem. 89, 1716￿1723 (2017) DOI: 10.1021/acs.analchem.6b03943
  • D.K. Singh, O. Gholamalamdari, X.L. Li, A. Chakraborty, Y. Zhang, S. Guang, S. Hashemikhabir, S. Tiwari, A. Thomas, V. Macias, A. Kadjacsy-Balla, R. Bhargava, S.C. Janga, J. Ma, S.G. Prasanth, A. Lal, K.V. Prasanth ￿PSIP1 promotes tumorigenicity in breast cancer cells by regulating the expression of genes controlling cell cycle progression￿ Carcinogenesis 38(10), 966-975 (2017) DOI: 10.1093/carcin/bgx062
  • I.L. Rasskazov, N. Spegazzini, P. S. Carney, R. Bhargava ￿Dielectric Sphere Clusters as a Model to Understand Infrared Spectroscopic Imaging Data Recorded from Complex Samples￿ Anal. Chem. 89, 10813￿10818 (2017). DOI: 10.1021/acs.analchem.7b02168
  • A. Ghosh, P. Mukherjee, S. Deb, R. Bhargava ￿Mapping Solvation Environments in Porous Metal Organic Frameworks with Infrared Chemical Imaging￿ J. Phys. Chem. Lett. 8, 5325￿5330 (2017). DOI: 10.1021/acs.jpclett.7b02104
  • A.M. Andrews, R. Bhargava, R. Kennedy, L. Li, J.V. Sweedler ￿The Chemistry of Thought: The Role of the Measurement Sciences in Brain Research￿ Anal. Chem. 89, 4757−4757 (2017)
  • A. Ganguli, A. Ornob, N. Spegazzini, Y. Liu, G. Damhorst, T. Ghonge, B. Thornton, C. J. Konopka, W. Dobrucki, S. E. Clare, R. Bhargava, A. M. Smith, F. Kosari, R. Bashir ￿Pixelated spatial gene expression analysis from tissue￿ Nat. Comm. 9, Art. number: 202 (2018)
  • R. Mankar, M.J. Walsh, R. Bhargava, S. Prasad, D. Mayerich ￿Selecting optimal features from Fourier transform infrared spectroscopy for discrete-frequency imaging￿ Analyst In press (2018)
  • T.P. Wrobel, R. Bhargava ￿Infrared spectroscopic imaging advances as an analytical technology for biomedical sciences￿ Anal. Chem. In press (2018)

Invited Lectures

  • R. Bhargava, S. Deb, A. Ghosh, A. Balla ￿Stimulated Raman Scattering Microscopy for prostate pathology￿
  • R. Bhargava, S. Tiwari, S. Mittal ￿Infrared microscopy for rapid histopathology￿ SPIE Photonics West, February 2018
  • R. Bhargava, K. Yeh ￿Fast infrared chemical imaging for spatially-resolved sensing￿
  • R. Bhargava ￿Fourier transform infrared spectroscopic imaging for digital pathology￿
  • R. Bhargava, S. Tiwari ￿Extracting information from high dimensional chemical imaging data￿
  • R. Bhargava ￿Chemical imaging ￿ a new tool for digital molecular pathology￿
  • R. Bhargava, S. Mittal, K. Yeh ￿Discrete frequency infrared imaging for practical histopathology￿
  • R. Bhargava, S. Mittal, K. Yeh, S. Tiwari, A. Balla, J. Raman ￿Tissue microarrays, high-definition imaging, metrics, discrete frequency spectroscopy and tumor biology: Developing a protocol for practical histopathology using IR imaging￿ [Opening Plenary]
  • R. Bhargava ￿Emerging Optical Chemical Imaging Technology for Brain Histopathology￿
  • R. Bhargava ￿Rapid, High Quality Infrared Spectroscopic Imaging for Clinical Translation￿
  • R. Bhargava ￿Chemical Imaging ￿ a New Technology for Digital Molecular Pathology￿ [Keynote address].
  • R. Bhargava, T. Wrobel, S. Mittal ￿Towards practical IR imaging for rapid digital molecular pathology￿
  • R. Bhargava, K. Yeh, S. Mittal, S. Tiwari ￿Infrared imaging systems for digital pathology￿ [Keynote address]
  • R. Bhargava, K. Yeh, S. Tiwari ￿Discrete frequency vibrational spectroscopic imaging: development and prospects￿
  • R. Bhargava, T. Wrobel, L.S. Leslie, S. Mittal ￿Towards practical translational protocols with infrared spectroscopic imaging￿ ACS Fall Meeting, Philadelphia, August 2016
  • R. Bhargava, S. Kenkel, A. Ghosh ￿Biochemical nanostructural measurements for modeling of infrared and Raman spectroscopic responses￿
  • R. Bhargava ￿Advances in infrared spectroscopic imaging technology￿
  • R. Bhargava ￿Fast high-definition infrared spectroscopic imaging for practical histopathology￿
  • R. Bhargava ￿Infrared spectroscopic imaging: Towards rapid and clinically relevant imaging￿
  • R. Bhargava ￿Infrared microscopy for practical biomedical imaging￿
  • R. Bhargava ￿Infrared spectroscopic imaging ￿ emerging opportunities and challenges￿ [Plenary]
  • R. Bhargava ￿Infrared spectroscopic imaging for biomedical use￿
  • R. Bhargava ￿Pushing analytical limits of infrared spectroscopic imaging￿
  • R. Bhargava ￿Infrared spectroscopic imaging for biomedical diagnostics￿
  • R. Bhargava ￿Infrared microscopy for practical histopathology￿
  • R. Bhargava ￿Fundamental science-driven infrared spectroscopic imaging for clinical diagnostic systems￿
  • R. Bhargava ￿Discrete frequency spectroscopic imaging for fast chemical imaging of composite polymers￿
  • R. Bhargava ￿Extracting accurate molecular spectroscopic information from spatial structure modeling of tissue￿ SciX 2014, September 2014.
  • R. Bhargava ￿Chemical imaging for digital molecular pathology￿ [Plenary].
  • R. Bhargava ￿From correlative to predictive technology￿The impact on pathology of fundamental advances in spectroscopy￿ [Plenary].
  • R. Bhargava ￿Spectroscopic imaging for tissue analysis￿From theory to therapy￿
  • R. Bhargava, K. Yeh ￿High-resolution mid-infrared micro-spectroscopic imaging with a broadly tunable quantum cascade laser￿
  • R. Bhargava ￿Modeling spectroscopic imaging optical paths for new biomedical sensing opportunities￿
  • R. Bhargava ￿Moving infrared spectroscopic imaging to routine histopathologic analysis by fundamental advances in instrumentation and understanding￿ [Plenary].
  • R. Bhargava ￿Frontiers and challenges in infrared spectroscopic imaging￿
  • R. Bhargava, R. K. Reddy, K. Yeh, T. van Dijk, P. S. Carney ￿Theory and simulation to establish the foundation of vibrational spectroscopic imaging for cancer pathology" Pittcon 2013, Philadelphia, March 2013.
  • R. Bhargava, S. E. Holton, M. J. Walsh, A. Balla ￿Tissue histopathology￿Spectroscopic imaging technology development towards real-time decisions￿
  • R. Bhargava, T. van Dijk, P. S. Carney, M. Kole, M. V. Schulmerich ￿Combining theory and instrumentation for Raman imaging" EAS, Somerset, November 2012.
  • R. Bhargava, P. S. Carney, R. K. Reddy, M. J. Walsh ￿High resolution IR imaging: Theory and practice"
  • R. Bhargava, P. S. Carney, R. K. Reddy, K. Yeh, T. van Dijk, M. Gelber, M. V. Schulmerich ￿Advancing infrared microscopy instrumentation by theory and computation￿
  • R. Bhargava, P. S. Carney, R. K. Reddy ￿Infrared spectroscopic imaging: the next generation￿
  • R. Bhargava ￿Chemical imaging: An emerging paradigm in biomedical imaging￿
  • R. Bhargava, P. S. Carney, B. J. Davis ￿Infrared microscopy for forensic applications: An emerging technology aided by fundamental optical theory￿
  • R. Bhargava, A. K. Kodali, X. Llora, R. K. Reddy, M. J. Walsh, P. S. Carney ￿Development of highly sensitive and specific vibrational spectroscopic imaging guided by new theory￿
  • R. Bhargava, M. J. Walsh ￿Chemical imaging for histopathology: An emerging route for molecular and structural analysis of tissues￿
  • R. Bhargava ￿Advances in chemical imaging promise new opportunities for materials analysis￿
  • R. Bhargava, T. van Dijk, R. K. Reddy, P. S. Carney ￿Theory of resolution and image quality in mid-IR imaging￿
  • R. Bhargava, A. Balla, M. J. Walsh, J. T. Kwak, M. V. Schulmerich ￿Developing chemical imaging from single molecule to massively multiplexed sensing for pathology￿
  • R. Bhargava, A. K. Kodali, X. Llora ￿Engineering surface plasmons for controlled optical spectroscopic response in nanostructured particles￿
  • R. Bhargava, M. V. Schulmerich, M. Kole, R. K. Reddy ￿Infrared spectroscopic imaging with emerging sources￿
  • R. Bhargava, M. J. Walsh, R. K. Reddy, J. T. Kwak, A. Balla ￿Chemical imaging for histopathology￿
  • R. Bhargava, M. V. Schulmerich, R. K. Reddy, M. J. Walsh ￿Chemical imaging for histopathology￿
  • R. Bhargava, M. J. Walsh, F. N. Pounder, A. Balla, R. K. Reddy ￿Infrared spectroscopic imaging for label-free biomedical informatics￿
  • R. Bhargava ￿Infrared spectroscopic imaging: A new direction for an old chemical imaging technique￿
  • R. Bhargava ￿Chemical imaging for histopathology￿
  • R. Bhargava ￿Systems pathology with infrared spectroscopic imaging￿
  • R. Bhargava, M. V. Schulmerich, A. K. Kodali, R. K. Reddy and M. J. Walsh ￿Chemical imaging for automated histopathology￿ Eastern Analytical Symposium, Somerset, November 2010.
  • R. Bhargava, M. V. Schulmerich, A. K. Kodali, X. Llora, R. K. Reddy, M. Kole ￿Using computational modeling to improve biomedical Raman microscopy￿
  • R. Bhargava ￿Chemical imaging for molecular pathology￿
  • R. Bhargava, R. K. Reddy, J. Ip, F. N. Pounder, M. V. Schulmerich, D. Mayerich, X. Llora, R. Kong, M. J. Walsh ￿Infrared spectroscopic imaging for label-free and automated histopathology￿
  • R. Bhargava, A. K. Kodali, M. V. Schulmerich, X. Llora and R. K. Reddy ￿Integrating physics with chemometrics for enhanced vibrational spectroscopic imaging￿ [Meggers Award symposium].
  • R. Bhargava, M. V. Schulmerich and R. K. Reddy ￿Discrete frequency infrared spectroscopic imaging with a quantum cascade laser￿Rationale and potential￿
  • R. Bhargava, P. S. Carney, R. K. Reddy, A. K. Kodali ￿Modeling distortions in infrared spectroscopic imaging￿
  • R. Bhargava ￿Enabling prostate pathology with infrared spectroscopic imaging￿A roadmap for clinical translation￿ (Plenary opening lecture).
  • R. Bhargava ￿Non-perturbing cancer diagnostics using infrared spectroscopic imaging￿
  • R. Bhargava ￿Progress towards cancer pathology using infrared spectroscopic imaging￿
  • R. Bhargava ￿Enabling systems pathology by infrared spectroscopic imaging￿
  • R. Bhargava ￿Pathology without pathologists?￿
  • M. Schulmerich, A. Kodali, B. Davis, L. J. Elgass, R. Bhargava* ￿Raman microscopy of layered materials for improved localization of the Raman signal￿
  • Bhargava, R. K. Reddy, M. Schulmerich, A. K. Kodali, F. N. Pounder B. J. Davis ￿Next-generation infrared imaging for biomedical spectroscopy￿
  • R. Bhargava, J. Ip, A. K. Kodali, F. N. Pounder B. J. Davis ￿Ultrafast IR imaging for biomedical applications￿ (Plenary Lecture).
  • R. Bhargava ￿Imaging: Does it really offer more than ￿just￿ pretty pictures￿
  • R. Bhargava, R. K. Reddy ￿The critical role of controlled quality of spectral information and sampling on automated histologic recognition￿
  • R. Bhargava, F. N. Pounder, X. Llora, R. K. Reddy ￿Enhancing the tissue segmentation capability of fast infrared spectroscopic imaging via chemometric methods￿
  • R. Bhargava, F. N. Keith, R. K. Reddy, A. K. Kodali ￿Practical infrared spectroscopic imaging instrumentation for translating laboratory results to clinical settings￿
  • R. Bhargava ￿Spectroscopic imaging for an automated approach to histopathologic recognition in prostate tissue￿
  • R. Bhargava, R. K. Reddy, A. K. Kodali ￿Ultrafast mid-infrared spectroscopic imaging by combined computational and experimental optimizations￿
  • R. Bhargava, R. K. Reddy, R. Kong, G. Srinivasan ￿Engineering practical protocols for histopathology of human tissues and models using infrared spectroscopic imaging￿
  • R. Bhargava, R. Kong ￿FTIR spectroscopic imaging for evaluating engineered phantoms and tissues￿
  • R. Bhargava, F. N. Keith, G. Srinivasan, R. K. Reddy, R. Kong ￿FTIR imaging for pathology￿
  • R. Bhargava, F. N. Keith, G. Srinivasan, R. K. Reddy, R. Kong ￿Practical aspects of automated histopathology using FTIR Imaging￿
  • X. Llora, R. K. Reddy, B. Matesic, R. Bhargava* ￿Towards better than human capability in diagnosing prostate cancer using infrared spectroscopic imaging￿
  • R. Bhargava, F. N. Keith, G. Srinivasan, R. K. Reddy, R. Kong ￿Mid-infrared spectroscopic imaging for automated cancer pathology￿
  • I. W. Levin, R. Bhargava ￿Fourier-transform infrared histopathologic imaging: A practical protocol￿
  • R. Bhargava, G. Srinivasan, R. Reddy, X. Llora, R. Kong ￿FTIR spectroscopic imaging for cancer pathology￿
  • R. Bhargava ￿Advances in infrared imaging: Making sense of speed, noise and vibrations￿
  • R. Bhargava, F. N. Keith, R. Kong, A. Priya ￿Data processing for cancer diagnoses from IR spectral data￿
  • I. W. Levin, N. J. Crane, S. W. Huffman, S. M. Hewitt, R. Bhargava ￿Applications of vibrational and visible reflectance tissue pathology and tissue perfusion￿
  • E. G. Bartick, D. K. Williams, H. Peters, N. Crane, R. Schwartz, R. Bhargava, I. W. Levin ￿Spectrochemical analysis and spectral imaging of latent fingerprints and evidence included within the prints￿
  • R. Bhargava, I. W. Levin ￿Fourier transform infrared spectroscopic imaging for biomedical diagnostics: A high throughput approach￿
  • I. W. Levin, S. W. Huffman, S. Schlucker, D. C. Fernandez, R. Bhargava ￿Vibrational spectroscopic imaging: From macromolecular assemblies to biological tissues￿
  • I. W. Levin, S. W. Huffman, S. Schlucker, D. C. Fernandez, S. M. Hewitt, R. Bhargava ￿Infrared and visible reflectance spectroscopic imaging for tissues￿
  • S. M. Hewitt, R. Bhargava, S. W. Huffman, S. Schlucker, D. C. Fernandez, I. W. Levin ￿Application of spectroscopy to archival pathology material￿
  • I. W. Levin, S. W. Huffman, Q. Li, S. Schlucker, R. Bhargava ￿Biomolecular heterogeneity at the membrane and tissue level extremes: Vibrational spectroscopy using single-element and imaging detection￿
  • I. W. Levin, S. W. Huffman, S. Schlucker, D. C. Fernandez, S. M. Hewitt, R. Bhargava ￿Vibrational spectroscopic imaging: Prostate and esophageal histopathology￿
  • I. W. Levin, S. W. Huffman, R. Bhargava, D. C. Fernandez, K. J. Zuzak ￿Biomedical applications of infrared and visible reflectance spectroscopic imaging: From bench to bedside￿ (Meggers Award Address￿first three authors invited).
  • R. Bhargava, S. W. Huffman, S.-Q. Wang, I. W. Levin ￿FTIR spectroscopic imaging with fast focal plane array detectors￿
  • I. W. Levin, D. C. Fernandez, S. W. Huffman, K. J. Zuzak, R. Bhargava ￿Approaches to infrared and visible reflectance spectroscopic imaging￿
  • R. Bhargava, D. C. Fernandez, I. W. Levin ￿Fourier transform infrared spectroscopic imaging for biomedical diagnostics: An integrative paradigm￿ (Plenary Lecture)
  • R. Bhargava, D. C. Fernandez, S. W. Huffman, Steven M. Hewitt, Ira W. Levin ￿Infrared spectroscopic imaging for biomedical diagnostics￿
  • S. W. Huffman, R. Bhargava, S. Schluker, I. W. Levin ￿High fidelity infrared spectroscopic imaging of dynamic processes￿
  • R. Bhargava, S. W. Huffman, M. D. Schaeberle, D. Fernandez, I. W. Levin ￿Fourier transform infrared spectroscopic imaging methods for biomedical diagnostics￿ (Royal Society of Chemistry Symposium).
  • I. W. Levin, D. C. Fernandez, M. D. Schaeberle, S. W. Huffman, K. J. Zuzak, R. Bhargava ￿Approaches to infrared and visible reflectance spectroscopic imaging￿
  • R. Bhargava, M. D. Schaeberle, D. C. Fernandez, I. W. Levin ￿FTIR imaging of biological tissue for histopathological analyses￿
  • I. W. Levin, M. D. Schaeberle, D. C. Fernandez, R. Bhargava ￿FTIR spectroscopic Imaging of biological systems￿
  • R. Bhargava, I. W. Levin ￿New insights into old problems using FTIR imaging￿
  • R. Bhargava, M. D. Schaeberle, D. C. Fernandez, I. W. Levin ￿Fourier transform infrared spectroscopic imaging of biological systems￿
  • J. L. Koenig, T. Ribar, R. Bhargava ￿FTIR imaging of polymer-solvent diffusion￿ (Meggers Award Address￿all authors invited)
  • J. L. Koenig, S.-Q. Wang, R. Bhargava ￿FTIR imaging of multiphase polymeric systems￿
  • B. G. Wall, R. Bhargava, C. M. Snively, J. L. Koenig* ￿Microspectroscopic imaging of polymers￿
  • J. L. Koenig, S.-Q. Wang, R. Bhargava ￿FTIR imaging of polymer interfaces￿
  • R. Bhargava, J. L. Koenig* ￿FTIR imaging of polymeric systems￿

Teaching Honors

  • AE3 Scholar, Academy for Excellence in Engineering Education (2005)
  • Incomplete Lists of Teachers Ranked as Excellent, 12 times (2006-present)
  • Accenture Outstanding Faculty Award for Undergraduate Advising (2007, 2009)
  • Everitt Award for Teaching Excellence (2009)
  • Teaching Academy Faculty Fellow in Engineering (2010, 2011, 2012)
  • Rose Award for Teaching Excellence (2012)

Research Honors

  • William F. Meggers Award, Society for Applied Spectroscopy (1999)
  • National Science Talent Search Scholar, NCERT, India (1989-1996)
  • The Undergraduate Research Award, IIT-D (1994)
  • The Roll of Honour for Outstanding Cumulative Contribution as an Undergraduate (1996)
  • Samuel H. Maron Award, Case Western Reserve University (1998)
  • Sigma Pi Epsilon Honor Society, Society of Plastic Engineers (2000)
  • Case Alumni Award for Best Graduate Spectroscopist (2000)
  • Gordon F. Kirkbright Bursary Award, Association of British Spectroscopists (2001)
  • William F. Meggers Award, Society for Applied Spectroscopy (2002)
  • Best Manuscript, Prominent Young Vibrational Spectroscopists' Issue of Vibrational Spectroscopy (2004)
  • Faculty Fellow, National Center for Supercomputing Applications (2006)
  • Bronze Medal, Human-Competitive Competition, GECCO07 (2007)
  • DoD Young Investigator, Prostate Cancer Research program (2007)
  • Fellow, Center for Advanced Study (2010)
  • Xerox Award for Faculty Research (2011)
  • Campus award for outstanding promotion and tenure dossier (2011)
  • FACSS Innovation Award (2012)
  • Craver Award (2013)
  • William F. Meggers Award, Society for Applied Spectroscopy (2014)
  • Fellow, Society for Applied Spectroscopy (2015)
  • Fellow, American Institute for Medical and Biological Engineering (2015)
  • Agilent Thought Leader Award (2016)
  • Beckman Vision and Spirit Award (2017)

Public Service Honors

  • Ramachandra Rao Dasari Lecture, Indian Institute of Technology, Kanpur (2008)
  • Society for Applied Spectroscopy National Tour Speaker (2008)