Primary Research Area
- Biological Physics
Professor Kuehn completed a Ph.D. in Chemical Physics at Cornell University studying on non-contact friction and magnetic resonance force microscopy. During his postdoctoral research Dr. Kuehn began work in biology at The Rockefeller University. There he pursued measurements of population dynamics in microbial communities and behavioral diversity in microbes.
For more information
The Kuehn lab makes quantitative measurements of ecological and evolutionary dynamics. Our research is directed towards understanding the fundamental principles governing dynamics in complex biological systems at two levels of organization. First, we use model microbial ecosystems to study stability, adaptation and function of microbial communities. Second, we study the structure of the map between genotypes and phenotypes in model microbial systems to discover the rule of adaptive evolution.
Selected Articles in Journals
- Frequency dependent microbial growth during cycles of feast and famine. Jason Merritt and Seppe Kuehn, arXiv (2017).
- Environment determines evolutionary trajectory in a constrained phenotypic space. David T. Fraebel, Harry Mickalide, Jason Merritt, Thomas Kuhlman and Seppe Kuehn. eLife. (2017);10.7554/eLife.24669
- Quantitative high-throughput population dynamics in continuous-culture by automated microscopy. Jason Merritt and Seppe Kuehn. Scientific Reports 6:33173?7, (2016)
- Strongly deterministic population dynamics in closed microbial communities. Zak Frentz*, Seppe Kuehn* and Stanislas Leibler. Phys. Rev. X. 5(4) 041014 (2015)
- Behavioral diversity in microbes and low dimensional phenotypic spaces. David Jordan*, Seppe Kuehn,* Eleni Ketifori and Stanislas Leibler. Proc. Nat. Acad. Sci 110 (34) 14018-14023 (2013).
- Microbial population dynamics by digital in-line holographic microscopy. Zak Frentz*, Seppe Kuehn*, Doeke Hekstra, and Stanislas Leibler, Rev. Sci. Instrum. 81, 084301 (2010).
- Dielectric Fluctuations and the Origins of Noncontact Friction. Seppe Kuehn, Roger F. Loring, and John A. Marohn, Phys. Rev. Lett. 96, 156103 (2006).
- Force-gradient detected nuclear magnetic resonance. Sean R. Garner, Seppe Kuehn, Jahan M. Dawlaty, Neil E. Jenkins, and John A. Marohn, Appl. Phys. Lett. 84, 5091 (2004).
- Scialog Fellow. Moore Foundation/Research Corporation. 2015-2017.
- Postdoctoral Fellowship, Helen Hay Whitney Foundation. 2009-2012.
- Tunis Wentink Award for outstanding Ph.D. thesis. Cornell University. 2007