New Book: Mechanobiology of Cell-Cell and Cell-Matrix Interactions
Amy Wagoner Johnson, mechanical science and engineering, and Brendan Harley, chemical and biomolecular engineering, are co-editors of a new book, just published by Springer, that focuses on characterization and modeling of interactions between cells and their local extracellular environment.
Mechanobiology of Cell-Cell and Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines.
Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.
The book is organized into four technical sections that roughly reflect the organization of technical sessions at the SES symposium: Mechanisms of cell adhesion and mechanotransduction; cooperative cell behavior and mechanobiology; mechano-pathology of disease; and tools for exploring mechanobiology.
Contact: Amy Wagoner Johnson, Department of Mechanical Science and Engineering, 217/265-5581.
Brendan Harley, Department of Chemical and Biomolecular Engineering, 217/244-7112.
Writer: Linda Conway, Department of Mechanical Science and Engineering.
If you have any questions about the College of Engineering, or other story ideas, contact Rick Kubetz, editor, Engineering Communications Office, University of Illinois at Urbana-Champaign, 217/244-7716.